The NEW FDA-Approved Solution to END Chronic Knee Pain Without Surgery or Steroids.

Take our free 10 Second Quiz and find out if you qualify for a complimentary knee pain exam and consultation regarding this NEW, NON-SURGICAL KNEE PAIN TREATMENT that is FDA APPROVED and COVERED BY MEDICARE and Most Insurances.
**We ARE NOT In Network With CarePlus insurances.
Dr. John Burress, DO
Dr. John Burress is a third-generation Central Floridian with backgrounds in biology, neuropsychology, and osteopathic medicine, and has completed training with the Cleveland Clinic and Mayo Clinic. He is double board-certified in Family Medicine and Venous and Lymphatic Medicine and is pursuing a third board certification in Stem Cell and Regenerative Medicine. Dr. Burress has successfully treated thousands of osteoarthritis and knee pain patients using innovative regenerative treatment protocols, helping patients reduce their knee joint pain symptoms by 80-90% or more, and is passionate about helping knee pain patients find long-term relief without surgery.
Proudly serving Lady Lake, FL and the Villages and surrounding communities!
Surgery, Knee Replacements, Steroids, and Prescription Drugs are NOT REQUIRED In Finding Relief From Knee Pain. A NON-SURGICAL SOLUTION Is Now Available!
This Proven Non-Surgical Solution Is Helping Knee Pain Suffers:
**We ARE NOT In Network With CarePlus insurances.
The Proof Is In Our Patients
Read our

5-Star Patient Reviews
Joseph Towne
Read More
It is so hard to find a private practice primary care doctor. I am so pleased with the care team and Karen Callahan and Lady Lake Family Practice!! She is truly the best and takes the time to really understand your healthcare concerns. She is compassionate, kind and thorough. We recommend her to everyone!!
Joyce Johnson
Read More
I want to give HUGE SHOUT OUT TO KAREN CALLAHAN! She is the best..always listens to me, works with me to try different meds (without side effects), is very compassionate, caring and never ever tries to rush me or my visit. She always takes care of me and she always took care of my husband as well. Karen goes above and beyond!! ALL the staff are A1...so pleasant and easy to work with. I highly Recommend their services.
Howie Williams
Read More
My experience with the staff and my doctor Karen has been great. Karen takes her profession and the health and safety of her patients very serious. My experince with doctors in the past has been to shove you out the door as quickly as possible and move on to the next. So I stopped seeing doctors for years. This wasn't the case here. Karen took the time to get all of the important information and make sure I was on the right path giving me a referral somewhere she believed would be better suited as specialists in my needs.
Dawn Countermine
Read More
Everyone is great! I was sick and Karen didn't have any appointments available but I could see Hannah. Awesome person as well. Happy to say I am all recovered!! I recommend them highly, especially if you're new to the area like I am!
Brandi Villalobos
Read More
Karen Callahan, ARNP has more empathy and compassion than any MD I have ever been to!!! She listens and truly cares about giving the best treatment. I would not trade her for any Doctor!! This place has the very best nurses and office staff! It is where to go for outstanding health care.
Janice Barbour
Read More
Knee clinic - if you have knee pain, call this office. they are professional, kind and accommodating. Highly recommend. The staff is the best in the area. My knee pain is almost completely gone. I am able to walk again. Thank you, Dr. Burress and staff.
Janet Adam
Read More
I have tried several doctors in the area over my years in this area. I’m happy to say I would refer this practice hands down. Wounderful caring people work there. Unhappy with your doctor you should give Lake Lake Family medicine a try. I’m glad I did.
Don Lowe
Read More
Practicing Pandemic Cautionary Procedures now to keep everyone safe. We Love This Place and know many of the Staff Personally for many years. I HIGHLY RECOMMEND THIS PRACTICE!
Danielle Garcia
Read More
I have finally found a pcp that cares about me! I have terrible doctor anxiety and the staff is just wonderful!
Ed Borchers
Read More
excellent receptionist very happy with my doctors

Barbara – “My knee pain is gone!”
“I had been experiencing knee pain for over 15 years and had difficulty walking and doing everyday tasks. Even driving wasn’t possible. I walked out of the office without knee pain for the first time in years…this treatment is a miracle!”

Dorothy – “My grandkids say thank you.”
“After years of not being able to play with my grandkids due to chronic knee pain, I knew that I had to find a solution. I didn’t want to go to surgery due to cost and months of recovery time. I’m now able to play with my grandkids whenever I see them, thanks to this new treatment option. I cannot thank you enough!”

Cindy – “I finally have my knees back.”
“Even after my first visit I got a tremendous amount of relief. After 4 weeks now my pain is gone completely. I had a combination of treatments that together worked extremely well, and my knees also feel much stronger and genuinely healthier overall. This has been life-changing!”

Gerald – “I’m not just back to walking…I’m running and exercising again too.” “I’ve been recommended knee surgery many times in the past, but didn’t want to go forward with surgery. After this treatment, I can walk, run and exercise freely. This treatment option is incredible!